Autologous engineering of cartilage

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Autologous engineering of cartilage.

Treatment of full-thickness damage to hyaline cartilage is hampered by the limited availability of autologous healthy cartilage and the lengthy, cost-prohibitive cell isolation and expansion steps associated with autologous cartilage implantation (ACI). Here we report a strategy for de novo engineering of ectopic autologous cartilage (EAC) within the subperiosteal space (in vivo bioreactor), th...

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Autologous Diced Cartilage in Nasal Septoplasty

Diced rib cartilage is an acceptable option in severe nasal deformities. We present our preliminary experience in KAMC in nasal septoplasties using the autologous diced costal cartilage. This is a retrospective study of the 22 cases who needed the autologous diced costal cartilage in our centre in 4 years. All our patients needed autologous diced rib cartilages. Twelve were wrapped with tempora...

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Importance of Floating Chondrons in Cartilage Tissue Engineering

BACKGROUND Dedifferentiation of chondrocytes remains a major problem for cartilage tissue engineering. Chondrocytes loss differentiated phenotype in in vitro culture that is undesired for repair strategies. The chondrocyte is surrounded by a pericellular matrix (PCM), together forming the chondron. PCM has a positive effect on the maintenance of chondrocyte phenotype during culture in compar...

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autologous diced cartilage in nasal septoplasty

diced rib cartilage is an acceptable option in severe nasal deformities. we present our preliminary experience in kamc in nasal septoplasties using the autologous diced costal cartilage. this is a retrospective study of the 22 cases who needed the autologous diced costal cartilage in our centre in 4 years. all our patients needed autologous diced rib cartilages. twelve were wrapped with tempora...

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Evidence-Based Efficacy of Autologous Grated Cartilage in Primary and Secondary Rhinoplasty

BACKGROUND There are numerous methods to mold and shape cartilage grafts for use in rhinoplasty. Each technique has advantages and disadvantages. We are going to introduce a new method for cartilage shaping with long lasting effects confirmed by follow up examination and pathologic evaluation. METHODS Grated cartilage was used in 483 patients. For 89 cases, it was wrapped in fascia and in 394 p...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2010

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0907774107